COST Action TD1004

COST logo

COST Action TD1004

"MC joint WG's MEETING"

London - October 28-30, 2012


Download Workshop Programme
Map of important sites

SCIENTIFIC PROGRAM

  • SUNDAY, 28th October 2012 - B5 Auditorium, Franklin-Wilkins Building Waterloo Campus
    • 14:00 - 14:15 : Opening presentation by Prof. Silvio Aime (University of Torino, Torino, Italy)
    • WG1 Imaging reporters for theranostic agents
    • 14:15 - 14:20 : Short introduction by WG1 leader Eva Jakab-Toth (CNRS, Orleans, France)
    • 14:20 - 14:35 : Imre Tóth (University of Debrecen, Hungary)
    • "Mixed ligand metal-complexes modelling anion binding: the hard aluminium(III) and the soft thallium(III)"
    • 14:35 - 14:50 : Hanno Schieferstein (Johannes Gutenberg-University, Mainz, Germany)
    • "Folate receptor targeted delivery of supramolecular drug-carriers monitored by PET"
    • 14:50 - 15:05 : Tobias Ross (Johannes Gutenberg-University, Mainz, Germany)
    • "Radiolabelling of TaOx nanoparticles for dual-modality imaging"
    • 15:05 - 15:20 : Jonathan Martinelli (University of Piemonte Orientale A. Avogadro, Italy)
    • "Host-guest paramagnetic supramolecular assemblies"
    • 15:20 - 15:35 : Stephane Petoud (CNRS, Orleans, France)
    • "Polymetallic lanthanide metal-organic frameworks for biological imaging in cells"
    • 15.35 - 15.55 : Coffee break
    • 15:55 - 16:10 : Alexandra Foucault (CNRS, Orleans, France)
    • "Near-infrared luminescent polyaminoamide lanthanide dendrimer for tumor diagnostic"
    • 16:10 - 16:25 : Rabha Kerdjoudj (Subatech,Nantes, France)
    • "Evaluation of 44Sc radiopharmaceuticals derived from DOTA-based phosphonic acids "
    • 16:25 - 16:40 : Edyta Leszczuk (Institute of Nuclear Chemistry and Technology, Warsaw, Poland)
    • "TiO2 nanoparticles as vehicles of 212Pb and 225Ac for internal radiotherapy"
    • 16:40 - 16:55 : Seweryn Krajewski (Institute of Nuclear Chemistry and Technology, Warsaw, Poland)
    • "44,43Sc and 47Sc as matched pair for theranostic approach to peptide receptor radionuclide therapy"
    • 16:55 - 17:10 : Sandip M. Vibhute (Max Planck Institute for Biological Cybernetics, Tübingen, Germany)
    • "Synthetic modification of pH sensitive contrast agents for attachment to functional molecules and its utilization in biotin-avidin system"
    • 17:10 - 17:25 : Dorothea Moderegger (Johannes Gutenberg-University, Mainz, Germany)
    • "Molecular imaging of HPMA-based drug carrier systems: Influence of size and polymer architecture on body distribution and tumor uptake in vivo"
    • 17:30 - 19:30 : MC meeting (for MC members and the MC substitutes)
  •  
  • MONDAY, 29th October 2012
    • WG2 Characterization of Nanocarriers for theranostic agents
    •  
    • 09:00 - 09:05 : Short introduction by WG leader Ruth B. Schmid (SINTEF, Norway)
      •  
      • Physico-chemical methods:
      • 09:05 - 09:20 : Neus Lozano (University College London, London, UK)
      • "Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues"
      • 09:20 - 09:35 : Elias Fattal (University Paris-Sud, France)
      • "Physico-chemical characterization of nanoparticles in regards to fate and toxicity"
      • 09:35 - 09:50 : Ulrich Schatzschneider (Julius-Maximilians-Universität, Würzburg, Germany)
      • "Strategies for the modular conjugation of bioactive functional groups to solid nanocarrier materials"
      • 09:50 - 10:05 : Aurélie Jacquart (CEA-Leti, Grenoble, France)
      • "Nanocharacterisation of Lipidots?"
      • 10:05 - 10:20 : Magdalena Stevanovic (Serbian Academy of Sciences and Arts, Belgrade, Serbia)
      • "Polyester micro- and nanospheres as carriers for different medicaments"
      • 10:20 - 10.35 : Vesa-Pekka Lehto (University of Eastern Finland, Kuopio, Finland)
      • "Characterization aspects of nanoporous inorganic materials"
      • 10:35 - 10:50 : Stefaan de Smedt (Ghent University, Belgium)
      • "Advanced fluorescence microscopy to study nanomedicines"
      • 10:50 - 11:20 : Coffee break & poster session
      • 11:20 - 11:35 : Maria Antonia Herrero Chamorro (University of Castilla-La Mancha, Spain)
      • "Chemical functionalization and characterization of carbon-based nanomaterials"
      •  
      • In vitro and in vivo models:
      • 11:35 - 11:50 : Maria José Alonso (University of Santiago de Compostela, Spain)
      • "Polymer nanostructures for overcoming biological barriers"
      • 11:50 - 12:05 : Francesca Baldelli Bombelli (University of East Anglia, Norwich, UK)
      • "Engineered nanoparticles: the bionano interface in a biological environment"
      • 12:05 - 12:20 : Maria Blanco Prieto (University of Navarra, Spain)
      • "Complete inhibition of extranodal dissemination of lymphoma by edelfosine-loaded lipid nanoparticles"
      • 12:20 - 12:35 : Karine Andrieux (University Paris-Sud, France)
      • "In vitro BBB models for studying nanoparticles translocation"
      • 12:35 - 12:50 : Huw Summers (Swansea University, Swansea, UK)
      • "Development of assays and models for a pharmacology of nanoparticle drug delivery vectors"
      • 12:50 - 13:05 : Khuloud T. Al-Jamal (Kings College London, London, UK)
      • "Magnetic carbon nanotubes for dual in vivo imaging"
      • 13:05- 14:05 : Lunch break & poster session
    •  
    • WG4 Theranostic agents responsive to endogenous and external stimuli
    •  
    • 14:05 - 14:10 : Short introduction by WG4 leader Gerben Koning (Erasmus Medical Center, Rotterdam, Netherlands)
    • 14:10 - 14:40 : David Needham (University of Southern Denmark, Odense, Denmark; Duke University, Durham, USA)
    • "Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors"
    • 14:40 - 15:00 : Adam Gormley (Imperial College London, London, UK)
    • "Light and heat guided drug delivery"
    • 15:00 - 15:20 : Ann Seynhaeve (Erasmus Medical Center, Rotterdam, Netherlands)
    • "Tumor vessel manipulation to improve drug delivery"
    • 15:20 - 15:40 : Chantal Pichon (Université d'Orléans, France)
    • "Ultrasound and microbubbles assisted- gene delivery: in vitro mechanistic investigations and in vivo efficacy"
    • 15:40 - 16:10 : Coffee break & poster session
    • 16:10 - 16:30 : Laila Kudsiova (King's College London, London, UK)
    • "Delivery of anionic vs. cationic lipopolyplexes to the brain via CED"
    • 16:30 - 16:50 : Olivier Tillement (Université de Lyon, France)
    • "Radiosensitizing effect of ultrasmall gadolinium based particles"
    • 16:50 - 17:10 : Wafa Al-Jamal (UCL School of Pharmacy, UK)
    • "Different hyperthermia protocols and their effect on drug release"
    • 17:10 - 17:30 : Zahraa Al-Ahmady (UCL School of Pharmacy, UK)
    • "Lipid-peptide vesicle nanoscale hybrids for triggered drug release by mild hyperthermia in vitro and in vivo"
    • 17:30 - 18:30 : Cheese and wine reception & poster session
  • TUESDAY, 30th October 2012 - Henriette Raphael Function Room Guy's Campus
    • WG4 Theranostic agents responsive to endogenous and external stimuli
    •  
    • 09:00 - 09:20 : Goran Angelovski (Max Planck Institute for Biological Cybernetics, Tübingen, Germany)
    • "Dynamic and target-specific MRI probes for neuroimaging"
    • 09:20 - 09:40 : Catharina de Lange Davies (NTNU, Trondheim, Norway)
    • "Ultrasound enhanced uptake and improved microdistribution of multifunctional nanoparticles in prostate tumours in mice"
    • 09:40 - 09:55 : Stanley Fokong (University of Aachen, Germany)
    • "Image-guided, targeted and triggered drug delivery to tumors using polymer-based microbubbles"
    • 09:55 - 10:10 : Silvia Rizzitelli (University of Torino, Italy)
    • "In vivo MRI visualization of the intratumor release of doxorubicin from liposomes by non focused ultrasound"
    • 10:10 - 10:40 : Coffee break & poster session
    •  
    • WG3 Preparation and selection of targeting vectors
    • 10:40 - 10:45 : Short introduction by WG3 leader Robert Muller (University of Mons, Belgium)
    • 10:45 - 11:05 : Sarah Belaïd (University of Mons, Belgium)
    •  
    • "Physicochemical properties of ultrasmall iron oxide nanoparticles synthesized by thermal decomposition"
    • 11:05 - 11:25 : François Lux (Université de Lyon, France)
    •  
    • "AGuIX: a new class of theranostic particles"
    • 11:25 - 11:45 : Maria Laura Bolognesi (Universitá di Bologna, Italy)
    •  
    • "A fluorescent small molecule with combined therapeutic and diagnostic activities against Alzheimer's and prion diseases"
    • 11:45 - 12:05 : Sijumon Kunjachan (RWTH Aachen University Clinic, Germany)
    •  
    • "Hybrid CT-FMT imaging of tumor vascular targeting"
    • 12:05 - 12:25 : Maria Garrido (University of Navarra, Spain)
    •  
    • "Targeting of epidermal growth factor receptor in colon cancer cell lines with PEGylated liposomes coupling to different ligands"
    • 12:25 - 12:45 : Twan Lammers (Universiteit Utrecht, Netherlands)
    • "Passive versus active targeting"
    • 12:45 - 14:05 : Lunch break and poster session
    •  
    • WG5 Set-up of preclinical theranostic protocols
    •  
    • 14:05 - 14:10 : Short introduction by WG5 leader George Loudos (Technological Educational Institute of Athens, Greece)
    • 14:10 - 14:30 : Tim Devling (iTheraMedical, Neuherberg, Germany)
    •  
    • "Multispectral Optoacoustic Tomography (MSOT) in drug delivery"
    • 14:30 - 14:50 : George Loudos (Technological Educational Institute of Athens, Greece)
    •  
    • "Initial experience from the assessment of magnetic hyperthermia effect using in vivo nuclear imaging"
    • 14:50 - 15:20 : Coffee break & poster session
    • 15:20 - 15:40 : Eirini Fragogeorgi (Technological Educational Institute of Athens, Greece)
    •  
    • "Preliminary in vitro and in vivo evaluation of a 99mTc labelled hybrid magnetic nanocarrier"
    • 15:40 - 16:00 : Rafael Torres M. de Rosales (King's College London, London, UK)
    •  
    • "Exploring potential applications of bimodal PET-MR nanoprobes in imaging and therapy"
    • 16:00 : Closing remarks by Prof. Silvio Aime (University of Torino, Torino, Italy)

POSTER PRESENTATION

  1. Florian Mayer, P. van der Est, R. Goverde and K. Djanashvili
  2. (Delft University of Technology, Netherlands),
  3. "Fluorogenic click reactions for nanoparticles functionalization".
  4. W. Zhang, F. Mayer, J.A. Peters and Kristina Djanashvili
  5. (Delft University of Technology, Netherlands),
  6. "Ln(III)-loaded zeolites for multimodal imaging".
  7. Ana C. Mendonça, André F. Martins, Andreia Melchiorre, Sérgio M. Marques, Sílvia Chaves, Stéphane Petoud, P.L. Zanonato, Marilena Tolazzi, Célia S. Bonnet, Éva Tóth, Plinio di Bernardo, Carlos F.G.C. Geraldes and M. Amélia Santos
  8. (University of Coimbra, Portugal),
  9. "New lanthanide complexes with a Tris-3,4-HOPO ligand, as new potential imaging probes".
  10. Lorenzo Tei
  11. (University of Piemonte Orientale A. Avogadro, Italy),
  12. "Small sized liposomes and discoidal micelles by incorporation of amphiphilic Mn(II) complexes".
  13. Mauro Botta
  14. (University of Piemonte A. Avogadro, Italy),
  15. "A novel ditopic Gd(III) complex functionalized with an adamantyl moiety".
  16. Célia Bonnet
  17. (CNRS, Orleans, France),
  18. "Zinc responsive agents".
  19. Michal Maurin
  20. (NCNR Radioisotope Centre POLATOM, Poland),
  21. "Preliminary results of 90Y radiolabelling of ultra small rigid particles as multimodal probes".
  22. Agata Piotrowska, E.Leszczuk and A.Bilewicz
  23. (Institute of Nuclear Chemistry and Technology, Warsaw, Poland),
  24. "Nanozeolite as a vehicle for 223,224,225Ra radionuclides".
  25. C. Tsoukalas, T. Tsotakos, M. Meckel, V. Kubicek, S. Xanthopoulos, P. Hermann, F. Roesch and P. Bouziotis
  26. (Demokritos, Athens, Greece),
  27. "Attempts toward the development of dual-modality imaging agents based on the conjugation of biphosphonates directly to the surface of superparamagnetic iron oxide nanoparticles".
  28. Zsolt Baranyai, Anett Takács, Balázs Podolyák, Mihály Purgel, Roberta Napolitano, Silvio Aime, Erno Brücher and Imre Tóth
  29. (University of Debrecen, Hungary),
  30. "Equilibrium, kinetic, relaxation and structural properties of H3DO3A-sulfonamide ligand and its Ca2+, Zn2+, Cu2+ and Ln3+-complexes".
  31. Ondrej Zemek, Jan Kotek and Petr Hermann
  32. (Charles University, Czech Republic),
  33. "Monophosphinic acid DOTA analog for click chemistry".
  34. Eva Jakab-Toth
  35. (CNRS, Orleans, France),
  36. "Liposomes and Lipoproteins as bimodal imaging probes".
  37. Silvia Fontenete, N. Guimarães, M. Leite, C. Figueiredo, J. Wengel and N.F. Azevedo
  38. (University of Porto, Portugal),
  39. "Nucleic acid mimics hybridization at human body temperature in Heliobacter pylori".
  40. Rita S. Santos, Nuno Guimarães, Pedro Madureira and Nuno F. Azevedo
  41. (University of Porto, Portugal),
  42. "Impact of the external cellular milieu on the diffusion and hybridization of nucleic acids in bacterial cells".
  43. Jussi Rytkönen
  44. (University of Eastern Finland, Finland),
  45. "Intracellular delivery of antisense oligonucleotides with porous silicon nanoparticles".
  46. Desire Di Silvio
  47. (University of East Anglia, UK),
  48. "Study of the interaction between protein corona nanoparticles and lipid bilayers as cell membrane models".
  49. Aarthi Rekha Devarajan
  50. (University of East Anglia, UK),
  51. "Hazard assessment of engineered nanocarriers using in vitro and in vivo toxicity studies".
  52. Francisco Silva, A. Zambre, Anónio Paulo, R. Kannan and Isabel Santos
  53. (Universidade Técnica de Lisboa, Portugal),
  54. "Multifunctional gold nanoparticles for theranostic applications".
  55. D. Stanicki, S. Laurent, L. Vander Elst, R.N. Muller
  56. (Umons, Belgium),
  57. "Flurophore-tagged iron oxide nanoparticles as bimodal contrast agents for MRI and optical imaging".
  58. E. Lipani, S. Laurent, M. Surin, L. Vander Elst, P. Leclère, R. Lazzaroni, Robert Muller
  59. (Umons, Belgium),
  60. "Characterization of biomedical nanomaterials for Magnetic Resonance Imaging".
  61. Tamara Cacev and Kapitanovic, S
  62. (Rudjer Boskovic Institute, Croatia),
  63. "Cancer as a challenge of the theranostic nanomedicine and Laboratory for Personalized Medicine (IRB)".
  64. Lydia Sandiford and Rafael T. M. de Rosales
  65. (King's College London, UK),
  66. "Bisphosphonate-anchored PEGylation and radiolabeling of superparamagnetic iron oxide: Ultra-stable nanoparticles for in vivo multimodal imaging".
  67. Javier Guerra, A.M. Herreros, C. Martín-Jiménez, M.D. Pérez-Carrión, F.C. Pérez-Martínez, J.C. García-Martínez, S. Merino. J. Tejeda, P. Sánchez-Verdú, V. Ceña, J. Rodríguez-López
  68. (University of Castilla-La Mancha, Spain),
  69. "Gold nanoparticles in assembled gene delivery carrier".
  70. Raha Ahmad Khanbeigi, Zeina Hashim, Mark Green, Helen Collins and Lea Ann Dailey
  71. (King's College London, UK),
  72. "Synthesis and safety assessment of conjugated polymer nanoparticles as photostable imaging agents".
  73. Wouter JM. Lokerse, Sarah Belaid, Sophie Laurent, Timo LM. ten Hagen, Alexander MM. Eggermont, Holger Gruell, Robert N. Muller and Gerben A. Koning
  74. (Erasmus Medical Centre, Rotterdam, Netherlands)
  75. "Magnetic nanoparticles for localized hyperthermia and controlled drug release in solid tumors".
  76. Michiel Bolkestein, Dubravka Drabek, Timo L.M. ten Hagen, Alexander M.M. Eggermont, Frank G. Grosveld and Gerben A. Koning
  77. (Erasmus Medical Centre, Rotterdam, Netherlands)
  78. "Immunoliposomes with single-domain antibodies targeted agains epidermal growth factor receptor (EGFR)".
  79. Michael Wright, Elena Rosca, Roman Gonitel, Andrew D. Miller, Wladyslaw Gedroyc and Maya Thanou
  80. (King's College London, UK)
  81. "Image-guided focused ultrasound for targeted anticancer drug delivery".
  82. Patrick Wilhelm, Carsten Kroll, Helmut R. Maecke and Helma Wennemers
  83. (Laboratory of Organic Chemistry, ETH Zürich, Switzerland)
  84. "Oligoproline as a molecular scaffold for tumor targeting"