Scuole

LLP
Socrates

Intensive Programme 2012

Probes and Models for Imaging Diseases and Therapy


Description

The purpose of the proposed Intensive Programme is to offer an in-depth training on how different imaging modalities, coupled with tailored imaging probes able to recognize specific pathologic markers, allow the visualization and quantification of disease evolution and the evaluation of therapy response. Teaching and practical sessions with hands-on experiments presented and supervised by scientists of the coordinating institution will be the backbone of the intensive programme. In addition lectures and lectures with practical demonstration will be implemented with the contribution of several partners of the project. The IP has been funded by the EU (contract n°: 2012-1-IT2-ERA10-38864)

This IP will be addressed to students in biology, biotechnology, chemistry, medicine or physics at one of the following levels:

  • Master students
  • PhD students (priority will be given to first year's students)
  • Undergraduate students who are expected to complete their bachelor studies by the end of September 2012

The participation of 20 students from the partner institutions will be supported by the EC Erasmus Programme. In order to apply for a scholarship, students will be asked to certify to be enrolled to one of the partner institutions. This will be asked at a later stage, after the selection procedure has been completed.

The Intensive Programme will be hosted at the Department of Chemistry of the University of Torino in the period September 17th-28th, 2012.

To apply: please see below at the application section.

  • Coordinator: Dario Longo
  • Assistant Coordinator: Paola Bardini
  • Coordinating Institution: University of Torino (Italy)
  • Location: Molecular Imaging Center, Via Nizza 52 - Torino (Italy)

Partners

INSTITUTION Local Coordinator Contact
UnipmnUniversitá degli Studi del Piemonte Orientale "Amedeo Avogadro" (I)Mauro Botta mail to
Univ Paris Sud 11 Université Paris sud 11 (F) Martine Raphael mail to
INSTN Institut National Des Science Et Technologies Nucleaires (F) Vivienne Fardeau mail to
Creete University of Creete (GR) Giannis Zacharakis mail to
VUB - Vrije Universiteit Brussel (B) VUB - Vrije Universiteit Brussel (B) Tony Lahoutte mail to
TUM - Technische Universität München (D) TUM - Technische Universität München (D) Markus Schwaiger mail to
Albert-Ludwigs-Universität Freiburg Im Breisgau (D) Albert-Ludwigs-Universität Freiburg Im Breisgau (D) Helmut Maecke mail to
Erasmus MC Rotterdam (NL) Erasmus MC Rotterdam (NL) Marion de Jong mail to
Universitat de Valencia (E) Universitat de Valencia (E) Luis Marti-Bonmati mail to


Location

The IP 2012 will take place from 17th to 28th September 2012. Lectures will be held at the Molecular Biotechnology Center, Via Nizza 52, Torino.

Students will be accommodated at EDISU, a student residence held by the University of Torino in Corso Lungo Dora Siena, 150, Torino and at Open011, a residence located in Corso Venezia, 11.

The following services are included:

  • Breakfast
  • Blankets, bed linen and towel (changed once every 7 days)
  • Cleaning (once every 7 days)
  • Free internet connection

Information on how to reach the location of the IP from airport or by train and on how to reach the lecture room from the residence will be sent to you by email.

Application

  • The application for our Intensive Programme must be made exclusively by submitting the registration form to the corresponding local coordinator. The deadline is set at 30th of August, 2012.
  • The selection procedures are undertaken by each Local Coordinator of the corresponding partner institutions, having a short interview with the candidate, so that the Local Coordinator verifies whether the applicants is well motivated and has the suitable background needed to attend the programme. This process will continue up to completion of the 20 available places. After the selection has been completed, the students awarded with the scholarship will receive an email with all the instructions for completing the registration procedure and for the participation. Students selected to participate without fellowship will also receive a message by email.
  • Scholarships are offered to students from the partner institutions. If you are applying for a scholarship, please notice that you will have to participate in all the 10 successive days of the programme. If you are planning to attend less than 10 successive days of the programme, you are not eligible for a scholarship and your expenses cannot be reimbursed.
  • In case you have been selected to participate in the IP (with/without fellowship), please submit the following document, saved as a pdf file:
    • copy of your passport (or id card for EU applicants).
    • an official document certifying your enrollment to a partner University for the current academic year.
    • flight electronic ticket (or a scanned copy of your flight ticket). Please notice that only tickets from/to your home institution can be reimbursed (this only applies to students who have been awarded a scholarship).

Additional info / News


Lecture notes and Program

Mon, 17th Tue, 18th Wed, 19th Thu, 20th Fri, 21th

9h30-11h00

Wellcome and IP introduction (Silvio Aime / Dario Longo) Preparation of radiolabelled probes (Frederic Dollé - Saclay/CEA) Radiopeptides for imaging and therapies (Helmut Maecke - Freiburg/Klinik Univ) Iron oxide particles (Robert Muller - Mons/Univ) Combined PET/MRI: where we stand (Markus Schwaiger - Munich/TUM)

11h30-13h00

Introduction to molecular imaging (Silvio Aime - Torino/Univ) Imaging probe designs and synthesis (Alessandro Barge - Torino/Univ) Platforms for drug delivery (Alessandro Maiocchi - Bracco Imaging SpA) Gd-complexes: from low MW to nanosized systems (Mauro Botta - Alessandria/Univ) CEST agents (Daniela Delli Castelli - Torino/Univ)

14h00-15h30

(Immune) Hallmarks of cancer (Federica Cavallo - Torino/Univ) Peptide synthesis and bioconjugation routes (Lorenzo Tei - Alessandria/Univ) MRI/NMR: introduction (Walter Dastrú Torino/Univ) Gd(III) complexes: basic relaxometric characterization (Eliana Gianolio - Torino/Univ) Responsive contrast agents (Giuseppe Digilio - Alessandria/Univ)

16h00-17h30

Medical image analysis (Alberto Bert - im3D SpA) Overview of peptide synthesizer and HPLC/LC-MS purification systems (Lorenzo Tei / Alessandro Barge) Design of imaging probes (Lorenzo Tei / Alessandro Barge) Relaxometric characterization of Gd(III) complexes and NMRD analysis (Eliana Gianolio / Simona Baroni / Francesca Arena) CEST experiment (Daniela Delli Castelli / Giuseppe Ferrauto)
Mon, 24th Tue, 25th Wed, 26th Thu, 27th Fri, 28th

9h00-10h30

DCE-MRI: principles and techniques (Dario Longo - Torino/Univ) Design MRI targeting agents (Simonetta Geninatti - Torino/Univ) Visit to Bracco Imaging facilities MRI: what is most in need in the clinics (Luis Marti Bonmati - Valencia/Univ) The study of molecular processes in living cells by fluorescence microscopy (Ferdinando di Cunto - Torino/Univ)

11h30-13h00

DCE-MRI at 1T (Dario Longo - Totino/Univ) Cell Labelling (Simonetta Geninatti - Torino/Univ) Visit to Advanced Accelerator Applications facilities (Immuno) Imaging using nano-bodies (Tony Lahoutte - Brussels/Univ) Imaging guided therapy (Enzo Terreno - Torino/Univ)

14h00-15h30

Hyperpolarized MRI: metabolic imaging (Alessandra Viale - Torino/Univ) targeting probes for PET/SPECT applications (Marion De Jong - Rotterdam/Erasmus MC) US imaging: basic principles and ecographic agents (Filippo Molinari - Torino/Politecnico / Enzo Terreno - Torino/Univ) Targeted therapies (Federica Cavallo - Torino/Univ) Hyperpolarized experiment (Francesca Reineri - Torino/Univ)

16h00-17h30

Imaging-guided therapy: the advent of theragnostic agents (Enzo Terreno - Torino/Univ) Optical imaging (Giannis Zacharakis - Crete/FORTH) Visit to CEIP FACS and Ab quantification (Elena Quaglino / Laura Conti) Final consideration and remarks / Final student assesments